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Am still here just have other things keeping me busy at the moment. Work is v.busy at the moment so have limited time to post. I'm still at work in the office as we speak and have been since 0800 this morning!
SK. Yet you post so often seeking it. ATB
SK And you do have influence? You do have a high opinion of yourself if you don’t mind me saying. How can I have called in wrong SK when my portfolio tells me clearly otherwise? So when you talk rubbish I’ll continue to post to highlight it. After all what’s the worst you can do. Shoot me with your bazooka? Again SK. You literally know nothing and it should be clear to anyone that choices to read your posts over the years. Keep up the good work. It’s very entertaining. ATB
You need to read posts knowlesi, not read who wrote them and decide what you want them to read. Anyway, glad you are some 400 percent up on your sub 5p buys here. Well judged.
I did not know Burble had left ......... i am sure he did not either , he is not a prolific poster like you Knowlesi ... maybe he is just busy
anyway well done on Games workshop and all the others you have done well in ..... sorry about the Pram Business ...
Just to clarify knowlesi, it is yourself you are talking about when you say 'You attempt to discredit in the hope you can manipulate vulnerable investors into being influenced by you.'
Knowlesi ... let me explain .. its about the number you hold ..
so if you invested £100,000 in Games workshop .... x 300% .... = shed loads ... then why fuss about a 1p at 4p in scancell ?
however if you had of invested £1000 x 300% ............. you might consider that 1p more important
Burble is fine what is the issue there ?
........Bermuda and myself still have email discussions and they are still amicable ...
Knowlesi i have filled my ISA 5 years on the trot with Scancell ........ suppose i could have bought Mothercare
the chart is the reason why we have so many shares now ..........
that is what you did not understand
SK. You know nothing. As I've said all along! Your days here are pointless. As Inanaco said. Its obvious who called this right. And you didn't..... ATB
Knowlesi .......... for the last two years you have been telling us we got it wrong ...
even Bermuda admits we called it right .......
SK. With respect if you had my portfolio I doubt you would feel desperate. Its very very healthy. So again keep up the (disrupting) work. It suits you. ATB
SK How can you be overlooked if you may be in discussions with another party? Just because another deal is announced the best you can say is that one big Pharma isn't talking to sclp. So its not a fact sclp have been overlooked is it? Buy hey ho most on here know your agenda so keep it up. ATB
so the next question ........... after this deal
https://www.fiercebiotech.com/biotech/genentech-lays-310-million-wager-biontech-s-mrna-cancer-vaccine-platform
produced
https://www.fiercebiotech.com/biotech/roche-biontech-post-low-response-rate-cancer-vaccine-trial
and to me each time they do this .......... The COST of a deal goes Up ........... not down
wonder if you have factored that into your Bazooka valuation
Knowlesi ................
clearly you have missed the point that its a "personal vaccine" .........
Through this partnership, Genentech and Vaccibody will progress Vaccibody's investigational product, VB10.NEO, into clinical trials in the U.S. and in Europe. VB10.NEO, an individualized DNA-based neoantigen vaccine, uniquely targets encoded antigens to antigen presenting cells which are essential for generating potent T cell responses required for cancer therapy. The vaccine is designed to be produced on-demand according to the neoantigen profile of an individual patient. Neoantigens are proteins generated by tumor-specific mutations not present in normal tissues, and are thus an attractive target for cancer immunotherapy as they may be recognized as foreign by the immune system.
""" uniquely targets encoded antigens to antigen presenting cells which are essential for generating potent T cell responses required for cancer therapy."""
when did they have the Uniquely bit ................... ?
Scancells targets direct to APC ......... and Cross presents
can you find that in the literature ?
perhaps not ..............
The deal is in the area of personalised vaccines that we know Lindy is not keen on.
Very expensive and time consuming.
Remember the project that Genentech and BionTech were involved in to find cancer targets that drew a blank. IMO this is why both companies are now concentrating on personalised vaccines.
But we do also know for a fact that both Genentech (Ira Mellman) and Biontech (Ugur Sahin) are interested in the Moditope targets. Scancell's strategy has been to prove the targets in clinical trials before considering deals.
As for IB, the strategy is the same albeit now based on trials in combination with a CI.
So IMO it is not a case of being the bridesmaid but saving yourself until you have developed an irresistible attractiveness to a very rich man :-)
GF,
I have no reason to believe Knowlesi does not have shares. I have no reason to believe you don’t hold a significant amount.
It is not surprising that when other companies in the same space are concluding deals that shareholders ask “why not us”.
As you rightly say, we don’t know what discussions are taking place and when a similar announcement for Scancell might come. When it does, let’s just hope it eclipses all those we have looked on with envy.
ATB.
Sk how do you know SCLP are not in discussions with anyone on a deal that's yet to be announced? Answer. You don't. Yet you are happy to try and knock a company you are supposedly invested in. Same old same old. ATB
Bit dramatic Knowlesi, And why the swipe at Inanaco??
Yes, it is certainly of interest. Obviously it is difficult to make comparison between two different companies who have perhaps slightly different approaches to different targets!
What we do know, is whatever it is they do, Genentech think it’s worth chucking £500m at.
That’s worth 70p per share in Scancell terms.
Yes Ruck,
Thought the commercial terms would be of interest here in “ valuing “ the science.
Whilst it seems good news in renewed interest in the cancer Vax space am not sure what implications it may have for validating the SCLP Approach or otherwise..
Thanks Ivy, I had found the news items.
$200m upfront and near term with $515m milestone payments. They won’t even be listed on the exchange until 7th October.
Makes Scancell look rather Tardy!