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Research progress
In recent years, the company has taken "Fruitflow® (water-soluble tomato concentrate)" as its main direction, focusing on the development of new functional products that help maintain cardiovascular health.
The project brought together domestic authoritative scientific research resources such as the Institute of Chinese Materia Medica of the Chinese Academy of Chinese Medical Sciences and the School of Public Health of Sun Yat-Sen University, and adopted By-Health ® Xinluo Su Tablets (the main functional ingredients are the same as those approved by EFSA, all are water-soluble tomato concentrates). Experimental samples, refer to domestic and foreign literature and methods approved and published by EFSA, and conducted in-depth investigations around related issues, and finally determined to establish a new function of "help maintain normal platelet aggregation and contribute to healthy blood flow". Animal function test evaluation of health food Methods and evaluation methods of the population test.
At present, this method has been repeatedly verified in Beijing Hospital, Peking University Third Hospital, Dongzhimen Hospital of Beijing University of Chinese Medicine, China Academy of Chinese Medical Sciences, Sun Yat-sen University and other domestic research institutions. The test results prove that the method has wide applicability, easy operation and detection. The results are reproducible. The project seeks safer antiplatelet substances to maintain normal platelet aggregation, reduces the risk factors for the occurrence and development of cardiovascular diseases, and makes an effective exploration for the research on new functions of health foods and the profound significance of maintaining public health.
In the future, the Institute will carry out more exploration and research in health areas such as reducing the end-products of glycosylation in the body to meet the health needs of different populations in different life cycles.
By-Health were ready to launch there first Fruitflow product in the second half of 2017 before deciding Blue Cap was the best way to go with it.
Studies in China were then required for Blue Cap submission and the last we were told was that BY-HEALTH were intending to make its first submission to the SAMR for Fruitflow® in February 2019. We all know that Blue Cap registration can be a slow process and the time scale is out with By-Healths control, 2 to 3 years has been quoted in previous info posted on here.
This is were it gets a bit vague . Currently there are 27 health functions in China most of which are not applicable to Fruitflow. One that is is "Assisting blood pressure reduction" and By-Health have a patent for a product that contains fruitflow to facilitate blood pressure reduction.
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020077747&_cid=P11-KJGTMR-22408-1
https://patentscope.wipo.int/search/en/detail.jsf?docId=CN238963528&_cid=P11-KJGTMR-22408-1
So a blood pressure reduction product would be a prime candidate (IMO) for the first Blue Cap submission.
We have been told By-Health will launch "a number of Fruitflow based products" but what health function out of the list of 27 can they then use?
In my opinion By-Health are not only in the process of obtaining Blue Cap for a fruitflow product but also trying to get a new health function into the Health Function Directory. What that will be I don't know but something like assisting the reduction of platelet aggregation might open up a lot more opportunities for Fruitflow in China.
All we can do is wait.
It's been nearly 5 years coming this November, since we first started working with byhealth ,still waiting for blue cup approval, its getting frustrating
Again, my reading of this is that the trades rarely take place at the extreme low or high points, but when they do it indicates to me where the next movement will be. With so large a spread there's nothing of interest for short term traders. This causes much lower volumes, meaning the MM's make very little income on trades. Bear in mind that each MM is trading hundreds of different shares, so having no turnover on any particular one doesn't trouble them. You must have noted that they try to anticipate major events such as scheduled updates, probable funding calls etc and move up or down ahead of what they think may happen. In that sense they are acting as traders do. If they have a big buyer, they know that and we don't, so they'll raise the Ask beyond what others want to invest at, and move the Bid around to try to accumulate the shares to fill the buy order. Alternatively, they can fill the order with shares they don't have, then drop the Bid sharply to trigger stops or panic sells. Nasty for us, but all in the game to them. MM's have much more power than PI's except in the case of a strung bull run, when they can be severely embarrassed. The famous case in US is an example, although I suspect that there were a few main actors whipping the gullible in to a frenzy.
I met a guy a while ago who worked in the markets sector for a major bank. He told me that most folks on the inside see PI's as mugs, to be separated from their capital whenever possible. It's for us to decide our actions in light of that knowledge IMHO
Asim Duttaroy new book.
Includes a section on Fruitflow.
https://www.elsevier.com/books/evidence-based-nutrition-and-clinical-evidence-of-bioactive-foods-in-human-health-and-disease/duttaroy/978-0-12-822405-2
32. Cardioprotective properties of water-soluble compounds of Tomato
Alfista,
You have explained the concept very well. However, the thing that I have never understood is the size of the bid offer spread that they use.
For example, the price quoted yesterday was: Bid 0.84 and Offer 1.0. The Bid/Offer spread was 19%. In fact, if you tried to trade yesterday (as I did) you will have noted that the actual trading prices were: Bid 0.84 and Offer 0.95. The actual Bid/Offer spread was 13%. However, I was completely put off trading because I didn;t want to look at an immediate 13% loss in the value of my investment.
Whichever you consider, the Bid/Offer spread that is quoted is still far too high to encourage investors to trade - and for the last week certainly there has been minimum volume whilst the spreads have been that wide.
On the other hand I have plotted significantly higher volumes when the spreads have been tightened.
Surely the MMs job is to encourage volume - they won't make any money unless shares are trading and we won't get a liquid market in the stock until that happens.
Thank you, very well explained
Responding to the headline price shown on here doesn't help your mood, so why not take a moment to study the trades, then you'll see that the sp rose slightly yesterday, due to MM's raising the Bid. At this time, with almost no trades, only the small adjustment non trades, the Bid and Ask are the only indicators of where MM thinking may be. They raised the Bid incrementally last week, keeping the Ask static. You may read this as meaning that they are slightly keener to buy shares than to sell them. MM's can, and do, short shares, hoping to push down the Ask and buy in shares to balance the books over a period. If no-one is selling, they have a problem, and have to raise the Bid. If still no-one sells, they have a real problem, but then they can go long, still without actually owning shares. Very complex, I'd still like to see a definitive cause of all those tiny trades.
All of the studies, and the continued mention of further brand take up, indicate to me that Fruitflow is still in the foothills of global development. I didn't know how long this would take. As far as I can assess, neither did anyone else, including the BoD and DSM/By Health. But we are getting there. IMHO
Thanks, but still pathetic!!
I don't think the bid or ask changed from open so mid is still the same but looks like the UT trade pulled us down.
Up 5.88% on the other side though.
https://www.lse.co.uk/ShareTrades.asp?shareprice=PXS.GB.PL&share=Provexis-Plc
£32.00 sold and SP goes down 8+% ridiculous
Released 2 days ago is hardly stale.
Been spoken about for months
This has gone very stale
Yes, he's been with them for many years.
:-)
Always IF WITH PXS
As the 19th July timeline for total lifting pandemic preventative measures in UK, this means we all will swim half naked in the sea of pandemic, some will have pants/bikinis on, some with life jackets on as well. So I suggest everyone should copy and paste the below message to multiple channels to highlight the potential of one more self saving measures in the form a daily food supplement tablet which might give one little extra strength to swim out of the sea of pandemic.
Platelet hyperactivity in COVID-19: Can the tomato extract Fruitflow® be
used as an antiplatelet regime?"
https://www.provexis.com/wp-content/uploads/2021/04/Platelet-hyperactivity-in-COVID-19-Can-the-tomato-extract-Fruitflow-be-used-as-an-antiplatelet-regime-04-Jan-21.pdf
"The new coronavirus causes excessive activation of platelets, and water-soluble tomato extract may relieve it"
Hi gixer,
Thanks for the great find. If PXS becomes a COVID-19 like SAR then sky is the limit here.
This is a post from BINH (BY-HEALTH Institute of Nutrition and Health) and refers to our review that was published in "Medical Hypotheses" magazine.
"Platelet hyperactivity in COVID-19: Can the tomato extract Fruitflow® be
used as an antiplatelet regime?"
https://www.provexis.com/wp-content/uploads/2021/04/Platelet-hyperactivity-in-COVID-19-Can-the-tomato-extract-Fruitflow-be-used-as-an-antiplatelet-regime-04-Jan-21.pdf
"The new coronavirus causes excessive activation of platelets, and water-soluble tomato extract may relieve it"
https://zhuanlan.zhihu.com/p/387011525
"This article was originally edited by the content team of BY-HEALTH Institute of Nutrition and Health"
Unfortunately there is a multi-party confidentiality arrangement surrounding Blue Cap and the launch of products by By-Health. So the chances of the company giving us any meaningful news on the progress is slim.
I suspect that that is for two reasons:
1 The dearth of news (even though there seems to be a lot going on in the background!!!)
2 The odd actions of the MMs in setting the share price, together with the wide bid/ask spreads. The spreads are beginning to make this an illiquid stock - whenever the spreads have been narrowed, shares have been traded - it is almost as if the MMs don;t want to trade shares
This is getting very boring share
Not sure I understand you everhopeful, wouldn't that only apply to shares that pay a dividend?
Otherwise wouldn't they donate cash and not shares?
Not sure in either case it would affect PXS.
Not a code , brokers tidy up accounts by donating to charity free of cost any shares not making a round number in cash.
Seen the claim so many times over the years, but never seen any proof that there is any such MM code.
No volume to get them interested at the moment