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I wish folk would read up in what they’re invested in - we are a challenge study businesses - enough said !
Government won't do these clinical studies by themselves, they will instruct clinical teams or corporations with experience. If they do choose to run themselves they will be likely shambolic, be delayed, suffer from such inertia from vested interests all chipping in they will be disastrous. They may sponsor some of the p3 trials for rapid action if future pandemic much like what we had in 2020 but we don't play in that space. We are much more focused on p1/p2. All completion is good as it drives awareness and acceptance but rocking up as a new player in CHIMS will be painful and need lots of work and capital. Moat is large for open orphan on this front. We have experience, expertise/staff and a portfolio advantage that would be better acquired for a large cro than to reinvent wheel. All adds to long term investment thesis.
Who said anything about human challenge trials either? The posted link was about trialling vaccines and diagnostics. Services which OO provide. Seriously. Although even ans scinv posted on 10th may, Anyone with enough money could do it and the government have lots of ours.
Zzzzzzzz yet another stupid conspiracy theory...I'm thinking of setting up some Human Challenge studies in my garden shed to compete with Open Orphan....
Nobody said it did? I posted the link and said there was a chance of the Government doing it themselves which could impact OO future income?
I am saying the link has nothing to do with hvivo/oo. It is neother positive nor negative. Other are doing challenge trials as well, but the link has nothing to do with that.
So are you saying the government couldn't take Orphs ideas and start doing trials, diagnostics etc themselves scinv?
Yes there is no relation whatsoever. I'm just allergic to BS
It's not just HCs, Its also diagnostics. I guess time will tell what they are up to.
Either way it doesn’t make the WHA competition in the HC market.
Timber it is none of those things. 1000s of clinitrials around the world every day. It is more about raising the standards i less developed countries.
Northseatiger - to the contrary. It presents a great opportunity to licence and/or sell ORPH’s HC study IP and know how to multiple countries.
Interesting to read follow up points. Apologies, thought everyone on here was quite clear re the Gov contracts or lack of by now. My thoughts were just that the paper NST cited imo just showed that govts and authorities will be investing in solutions worldwide and surely overall this is positive news rather than negative?
Link in the first comment has nothing to do with hvivo/OO.
Half-answering my own Q, here are extracts from wallyj's notes re 15 Mar 2022 presentation, suggesting CF is down-playing importance/prospects/likelihood of HMG takeup/follow-through....
.."Has ORPH had regulatory approval for Covid studies and how many companies are interested?
- Study has been published and peer reviewed, it will be in Nature magazine next week which reassures potential clients. Revenue will be on top of the £50m currently guided. A number of studies expected every year from commercial interests RATHER THAN GOVERNMENT [my bold]
£40m gov contract?
- Quite a lot of that money came to ORPH, BETTER to sign up multiple studies at up to £10m with pharmas, OTHER non-Covid studies are also approaching £10m mark now.."
Ho hum
Our government has more important priorities like building schools in India and ****stan because their governments need to spend money on their Nuclear weapons programmes...
PS, re .."just don’t understand what the U.K. Gov are playing at ..."
Quite agree : it's apparent from successive crises - that gubmint - of whatever political hue - is reactive to 'events, dear boy, events' .
Any manner of foreseeable issues - housing, inflation, energy shock, levelling up, NHS deficiencies - are unaddressed until there's a crisis.
Not just the pols, too : they're expected to have a short - term view ('the attention span of a gnat, to coin a phrase' ;-...) Where is the long-term strategic thinking that plans beyond the electoral cycle ?
I make it 1 CHIM study @ £ 10m (now completed) and 3 x downpayments @ £ 2.5m for further CHIMs, status unclear AFAIAA, they may have started 1 to compare 'original Wuhan' with 'Delta variant' (I think they're still working on the 'brew').
Maybe someone out there can quote chapter and verse ?
From RNS 20/10/2020... "The contract starts immediately and could be worth approximately GBP10 million to hVIVO depending upon the final number of volunteers that are included in the characterisation study. In addition, the Government has secured the first three slots to test vaccines using hVIVO's COVID-19 challenge study, which we expect start in 2021, each slot reservation has been secured at a cost of GBP2.5m each bringing the total value of these slot reservations to GBP7.5m..."
HTH
Hi NST 1 indeed still holding .My understanding is that the deposits paid…totalling £12.5 Million where paid ..and go straight to our bottom line ..just don’t understand what the U.K. Gov are playing at ..
Clinical trials are one thing, lots of companies do them all the time. Human challenge studies are a bit more specialised.
My take on it. fwiw :)
Think the business is a bit too complex to just half inch our ideas! I'm no expert but don't we have the staff, the chims & a moat?
Or maybe when we worked for them they stole Orphs ideas and decided to go alone. They've already defaulted on payment for services in other companies like ABDX etc and haven't paid us for the other 2 challenges yet
Imo as the World leader in human challenge trials and the obvious talent at our disposal I can only see the expansion of clinical trials worldwide as a positive. With the British Govt at the forefront of this objective, maybe we will be surprised & delighted at the role we might play?
So now we have the World Health Assembly as competition? Ffs
https://www.gov.uk/government/news/new-clinical-trials-deal-struck-to-better-protect-world-from-future-pandemics