George Frangeskides, Exec-Chair at Alba Mineral Resources, discusses grades at the Clogau Gold Mine. Watch the full video here.
London South East prides itself on its community spirit, and in order to keep the chat section problem free, we ask all members to follow these simple rules. In these rules, we refer to ourselves as "we", "us", "our". The user of the website is referred to as "you" and "your".
By posting on our share chat boards you are agreeing to the following:
The IP address of all posts is recorded to aid in enforcing these conditions. As a user you agree to any information you have entered being stored in a database. You agree that we have the right to remove, edit, move or close any topic or board at any time should we see fit. You agree that we have the right to remove any post without notice. You agree that we have the right to suspend your account without notice.
Please note some users may not behave properly and may post content that is misleading, untrue or offensive.
It is not possible for us to fully monitor all content all of the time but where we have actually received notice of any content that is potentially misleading, untrue, offensive, unlawful, infringes third party rights or is potentially in breach of these terms and conditions, then we will review such content, decide whether to remove it from this website and act accordingly.
Premium Members are members that have a premium subscription with London South East. You can subscribe here.
London South East does not endorse such members, and posts should not be construed as advice and represent the opinions of the authors, not those of London South East Ltd, or its affiliates.
Antelope, there have been ‘flu camps’ for most of the last century, where healthy volunteers are infected to study the effects of disease. Much of what we know about corona viruses comes from the Salisbury cold clinic, a former Red Cross hospital where volunteers would stay and ‘catch a cold’. There is of course no cure either for colds or flu, tens of thousands of people die of the latter each year. A ‘flu camp’ for otherwise healthy volunteers has never seemed unethical, given the advances that have been achieved through that study.
Yes antelope, that is exactly what they are saying, and it IS controversial. However, many academics have moved to the view that it is a justifiable risk in order to speed up the search for a vaccine, and potentially save millions of lives (1 million dead so far in 9 months, worldwide). There is obviously no antidote, otherwise the risk would not be necessary, but the antiviral drug remdevisir offers some relief in some cases. Only healthy young people would be infected, and the mortality rates in the younger age ranges are extremely low (but NOT zero). My understanding is that the study CF was offering to volunteer for was different - not for full blown COVID-19, but using a modified strain of another less harmful coronavirus to mimic the relevant elements of COVID-19: therefore essentially risk free. CF will certainly not be volunteering for the human challenge trials, and is anyway probably too old. If they get the go-ahead, the trials will probably run in parallel (timewise) with the final phase 3 tests of the leading vaccine candidates. It is only when a vaccine is actually released to the general public that it's true impact on a population can be fully assessed, which is why exhaustive testing is essential before that momentous step, and why human challenge trials can potentially speed up the process compared to testing on artificial substitutes.
CF also said that he is so confident in the safety of Hvivo's challenge study model that he would happily be the first volunteer.
CF has said in the past in response to a question on an investor webinar that it is far safer to get infected with Covid in a lab with a 10 - 20% viral load, compared to getting infected in the community with a viral load of up to 100%. Volunteers are also monitored at all times. CF also mentioned a 'rescue remedy' that can be given to the volunteers in the trial if needed but I don't think he specified which drug this was.
I'm sure I risk being laughed at for asking this, but if I need to, other newbies might also. The investor presentation and other sources suggest that human volunteers are 'infected' with various viruses as part of the process of evaluating vaccines. Surely they're not saying they actually infect people with covid... or other lurgies that there's no cure for. What am I not understanding?