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Pglancy
Yes see my apology on SBTX BB I mixed up Opti and SBTX and you were talking about selling Optis hares not SBTX.It was simply a mix up between the two shares nothing more sinister than that but of course I apologise for the mistake because accuracy is an obsession of mine.
'O fcourse the troll with a grudge nick plays the support role and wonders why he is 'hated.' Its not hate, its loathing and contempt because most of your effort is aimed at killing off avenues for investor communications with the company because you think you have the monopoly on the ability to read an rns. The sheer arrogance of you nick is putrid.'
1/ I don't wonder why I am hated and I did say universally hated, somebody said it . Not sure it's true not sure it's untrue. But I am not a troll (traitor). I am a shareholder (faithful). Cue Ms Winkleman
2/ I did nothing to cut off investor communication. I asked QUESTIONS of the nomad. The nomad did what he did. What else have I done towards 'killing off investor communications',?
3/ So I am 'hated' loathed held in contempt and now arrogant as well as putrid. wow. Monopoly on the ability to read an RNS? Where does that come from?
4/ I don't think I commented on aquas content. I did tick up actually and have thanked him in the past. FDA approval is difficult though.
5/ I do value the input of mol though, and like to support him. No way is he a troll (back to traitors) and I am appalled you think so. You need to control your anger.
PGlancy
This topic has nothing to do with the aqua research. Going to apologise? Title gives a clue.
Hi PG, yes accept that the labelling is the final outcome from the regulatory review. My interpretation of the progress reported in the RNS's is that the US Partner Mogroside based products have completed scale-up, undergone independent taste and structure analysis and hence the granulated version is ready for regulatory evaluation and classification for the Country a launch is aimed at. The fact that the initial launch is as a standalone product rather than as an ingredient incorporated in someone else's end product will simplify matters. Firmenich have yet to complete the optimised scale-up of their Stevenol based sweetbiotix products which I suspect will also need to undergo independent taste and structural tastes prior to any regulatory submissions.
Or they are as stupid as you mol. Thats my take on them voting up. They have not done the research aqua has, that's what those votes mean. Good spin though. Pathetic.
You can't make it up. The trolls see lemmings everywhere. Aqua goes into great detail helping investors understand the sugar labelling process in stateside and gets attacked by super troll mol. Instead of being grateful he uses the confession from aqua he communicated questions for lemmings to bat to SOH and get answers. Funny how that works so smoothly and hated by some self ritious trolls because all they have is hate for others work, craft and work. O fcourse the troll with a grudge nick plays the support role and wonders why he is 'hated.' Its not hate, its loathing and contempt because most of your effort is aimed at killing off avenues for investor communications with the company because you think you have the monopoly on the ability to read an rns. The sheer arrogance of you nick is putrid.
Aqua, i for one am grateful for your version of the lemming article. It was a very good supplement. However, i am not convinced sweetbiotix is down to just labeling stage of commercial viability.
Come on mol you are important here. Stop doing an impression of eeyore:). At least you are not universally hated as I am (post on Sbtx).
Topic titled podcast on sbtx dated 1/4/23 may help
Https://www.optibiotix-ir.com/content/news/archive/2023/190723
Yep read it - again
Still no FDA reference
I can just imagine texts, phone conversations , whats app
Whatever
I,m really not that important here - for the second time tonight
mol
Mol, read the 19th July RNS meeting the market need section and you will see mention of both the nutrional label and sweetbiotix as dietary fibers, all I have done is research the US label classifications to conclude what lies ahead once sweetbiotix are incorporated into suppliers products in the US
Aquae
I'm really not that important here and for you to take that reaction is - for the second time tonight - even more over the top
please continue to share your thoughts and have lemming thanks/hints on this bb
mol
Yes mol that all went quiet. Pretty sure someone on here will know something,?
Thx for that vote up whoever you are
at least not only shows you know who i was referring to but also , unfortunately perhaps , you have been here as long as i have
bw
mol
Mol the labelling mention is nothing to do with lemmings and if you have read the same RNS's and seen the Investor Meets presentations over the years you would be aware of the differently SOH has spoken of in terms of sweetbiotix being classified as sweet fibers rather than sugars. Also, the US nutritional labelling with added sugars has occurred relatively recently. All I have done is try and join the dots up for people once the penny dropped for me, perhaps with your unwarranted reaction I should not of bothered sharing my thoughts
Anyone?
lol
mol
Pity Stephen hasn't mentioned that once over 8 years and still hasn't to date as far as i know and of course the reason we are pursuing our path is to minimise regulatory hurdles...........
nevermind
if it's now only down to labelling
jees thank you for enlightening this bb on the wonderful world of lemmings and the self promotion and hints on here
i might just continue to post what i find foc or maybe not - lol
bw all
mol
Ensuring not insurance
Mol, the importance of insurance the structure, as opposed to just the flavour, had not been impacted by scale-up by an independent panel was so that it still qualified as an innovated dietary fibre. Hence part of the regulatory clearances that each finalised sweetbiotix product is subjected to, will include FDA labelling for the US market
AS, thanks for taking the time and trouble to share your questions and responses. And for reposting info on SweetBiotix and rivals' attempts at getting competing ingredients through regulation. And ultimately to market.
Is it possible SOH's doggedness and attention to detail will finally payoff? I hope so. And, let us not have to wait too much longer.
Whilst i note july 2022 rns and your extract
https://www.optibiotix-ir.com/content/news/archive/2022/200722
and i do note the contents
i draw your attention to the even more recent RNS update - which you and presumably other/s (who i guess prompted your long post) are very much aware of
https://www.optibiotix-ir.com/content/news/archive/2024/300124
and FDA labelling wasn't mentioned (FDA wasn't mentioned) - though perhaps important - not that important for inclusion in an RNS
whilst this was noted
In the last six months, there have been consumer concerns over sugar substitutes which has translated into existing and potentially new industry partners (including PepsiCo) discussing the use of natural, safe sugar substitutes like SweetBiotix® for both new and existing products. In anticipation of this need, OptiBiotix initiated development of its own finished product brands containing natural sugar substitutes and flavourings in mid-2023. The Company believe that natural products will be an increasingly common requirement throughout 2024 both in existing and new products. In recent months, products have been developed and successfully taste-tested with natural sweeteners for a large US company and a large Indian pharmaceutical company.
i await the launch of our own products in relation to our recent anticipation of this need - jees i thought that was the whole purpose of sweetbiotix some 6 years or more ago (c8 i think)
mol
Whilst on most occasions i very much appreciate your input Aquae
completely over the top this time
I've voted up your first succinct post and very much look forward to FDA product submissions re sweetbiotix but even more so news re products on sale this year
mol
Just thought I'd follow up on this group
https://optibiotix.com/optibiotix-announces-three-major-deals-with-partners-in-us-asia/
https://pierceesim.com/products-2/
as presumably three year deal exclusive has expired?
at least I haven't noticed to contrary by way of rns - perhaps missed something - which is possible
anyway perhaps someone here can enlighten us?
mol
Post 3 end
So bearing in mind Optibiotix Health recently announced that discussions are ongoing but are likely to involve a phased introduction of SweetBiotix® products as a direct bulk sugar substitute and the importance the FDA place on scientific evidence in classifying new products under the Innovative Dietary Fiber definition, the significance of the recent Independent verification of the structure and taste of scaled-up sweetbiotix from the US Partner, and the Optibiotix Health Commercial and Scientific Update RNS on 22nd July 2022 in supporting the Sweetbiotix application, cannot be understated.
“SweetBiotix® Publication: The Company is pleased to announce the publication of a study on the prebiotic activity and sweetness of one of its SweetBiotix® products in a peer reviewed journal (see https://pubs.acs.org/doi/10.1021/acs.jafc.2c01363). The study reports that enzymatic synthesis of modified mogroside and galacto-oligosaccharides (GOS) from lactose was able to generate products which positively modulated the microbiome with a sweetness profile similar to sugar. The products sweetness, bulking and prebiotic fibre properties could make it a suitable replacement to sugar in everyday products. This is one of a number of SweetBiotix® products developed for different application types in food, beverages, and dairy. Publications by independent authors in peer reviewed journals are critical in establishing industry awareness and credibility in the Company's products and provide valuable marketing assets to support product launches. “
https://pubs.acs.org/doi/10.1021/acs.jafc.2c01363
Post 3 continued
What evidence does the FDA use when determining whether an ingredient is classed as an innovative dietary fibre?
The FDA (U.S. Food and Drug Administration) evaluates evidence carefully when classifying a new ingredient as an innovative dietary fiber. Here are the key steps and considerations:
1. Scientific Research: The FDA reviews scientific articles that assess the physiological effects of the proposed ingredient. Researchers study how the ingredient interacts with the human body and its impact on health.
2. Elimination Process: Studies that do not provide clear scientific conclusions about the ingredient are eliminated from consideration. Only robust research is taken into account.
3. Beneficial Effects: The FDA evaluates the strength of evidence to determine whether the ingredient demonstrates beneficial physiological effects on human health. These effects must be relevant to dietary fiber.
4. Health Claims: If there is sufficient scientific support, the FDA may issue health claims related to the ingredient. For example, diets high in fiber-containing foods have been associated with reduced risk of certain cancers1.
5. Recent Additions: Over time, the FDA has added several isolated or synthetic non-digestible carbohydrates to the definition of dietary fiber. For instance:
◦ In December 2021, acacia (gum arabic) was included.
◦ In January 2020, glucomannan was added.
◦ In March 2019, cross-linked phosphorylated RS4 was recognized.
◦ In June 2018, the FDA responded to citizen petitions and identified eight fibers for potential inclusion2.
Remember, this process ensures that innovative dietary fibers meet rigorous scientific standards before being classified as such
Post 3 continued
So what does the FDA Class as Innovative Dietary Fibers?
The FDA defines innovative dietary fibers based on specific criteria. Let’s break it down:
1. Intrinsic and Intact Fibers:
◦ These are naturally occurring fibers found in plants, such as whole grains, fruits, and vegetables.
◦ They must be intrinsic (part of the plant’s structure) and intact (not significantly processed).
◦ Examples include cellulose, hemicellulose, and lignin.
2. Added Isolated or Synthetic Non-Digestible Carbohydrates (NDCs):
◦ These are non-digestible carbohydrates that are intentionally added to food products.
◦ To be considered dietary fiber, they must meet two criteria:
▪ Have at least 3 monomeric units (building blocks).
▪ Demonstrate beneficial physiological effects on human health.
◦ Companies must provide evidence of these health benefits to the FDA.
3. Examples of Added NDCs Recognized by the FDA:
◦ Acacia (gum arabic): Recently added to the list of dietary fibers 1.
◦ Glucomannan: Also recognized by the FDA 1.
◦ Cross-linked phosphorylated RS4: Another recognized fiber 1.
◦ These fibers contribute to the total dietary fiber content on nutrition labels.
4. Enforcement Discretion:
◦ While awaiting formal rulemaking, the FDA exercises enforcement discretion for certain fibers.
◦ Manufacturers can include the recognized fibers when calculating the amount of dietary fiber to declare on labels.
◦ For instance, polydextrose (a recognized fiber) is assigned a caloric value of 1 kcal/g 1.
In summary, the FDA classifies dietary fibers as either naturally occurring intrinsic fibers or added NDCs with proven health benefits. So, when you see “dietary fiber” on a label, it encompasses these diverse components!