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[The latest research suggests] there is no guarantee that a vaccine will be found that confers lasting immunity,” adds Stephen Evans, professor of pharmacoepidemiology at the London School of Hygiene and Tropical Medicine. “It’s possible immunity will be short-lived or even non-existent. We await the results of the trials.”
There are three other bits of emerging Covid science that vaccine teams are keeping a close eye on – two encouraging and one a bit terrifying.
On the bright side, the virus itself seems stable with no major mutations yet recorded which would derail vaccine development. And the focus of nearly all vaccine teams on disrupting the virus’s ‘spike protein’ looks correct, with more and more research showing its importance.
On the dark side, there is a “nagging concern” that the worst cases of Covid-19 could actually be linked to T-cells generated by the common cold, adds Dr Edwards.
A review in Nature described this as the risk of ‘original antigenic sin’, where the presence of T cells triggers an inferior immune response that actually makes the disease worse.
“There’s no indication that this is the case, but it’s just possible that some vaccine candidates will trigger an immune response that makes the virus more severe”, said Dr Edwards. “You just need to look at dengue fever… there are four types, and you almost always have a more severe disease after the second infection”.
Let’s hope Covid does not take after dengue.
Solicited adverse events that occurred in more than half the participants included fatigue, chills, headache, myalgia, and pain at the injection site. Systemic adverse events were more common after the second vaccination, particularly with the highest dose, and three participants (21%) in the 250-µg dose group reported one or more severe adverse events.
Hope your are right no more deaths and the economic chaos that the virus is causing would be welcome. Odx for me has potential, even post covid, POC testing is a growth area in many treatments as it cheap, reliable, quick and easy to use. For those who think Odx is not a good investment fair enough, do not invest, everyone does research and should know risk v reward
for a share and subsequent investment strategy, do what you feel comfortable with.
Vaccine will need a significant amount of the population to work.
100 micrograms dose and had lots of side affects.
There only studying 18 to 55 year olds and all participants in the test have been healthy
They haven't tested people with health issues.
Of a vaccine comes in mid winter . What then for ODX. I was looking to reinvest but think the sands of time are against ODX. https://www.nejm.org/doi/full/10.1056/NEJMoa2022483?source=nejmtwitter&medium=organic-social