We would love to hear your thoughts about our site and services, please take our survey here.
London South East prides itself on its community spirit, and in order to keep the chat section problem free, we ask all members to follow these simple rules. In these rules, we refer to ourselves as "we", "us", "our". The user of the website is referred to as "you" and "your".
By posting on our share chat boards you are agreeing to the following:
The IP address of all posts is recorded to aid in enforcing these conditions. As a user you agree to any information you have entered being stored in a database. You agree that we have the right to remove, edit, move or close any topic or board at any time should we see fit. You agree that we have the right to remove any post without notice. You agree that we have the right to suspend your account without notice.
Please note some users may not behave properly and may post content that is misleading, untrue or offensive.
It is not possible for us to fully monitor all content all of the time but where we have actually received notice of any content that is potentially misleading, untrue, offensive, unlawful, infringes third party rights or is potentially in breach of these terms and conditions, then we will review such content, decide whether to remove it from this website and act accordingly.
Premium Members are members that have a premium subscription with London South East. You can subscribe here.
London South East does not endorse such members, and posts should not be construed as advice and represent the opinions of the authors, not those of London South East Ltd, or its affiliates.
AZN , Sanofi I presume eyeing N4p and Curevac for its Vaccine delivery system expect collaboration as soon we find the cure for Covid 19...imo let's get an update as last spurt by 75% was not just at the back of P&D... there is potential for the Nuvec delivery system which is being developed to enhance any vaccine .
If anyone is tracking NSCI Netscientific I suspect they may be the next on the Covid19 bandwagon, they haven't as yet mentioned Covid19 but here is a link to what their COO of their subsidiary was posting yesterday on Linkedin I believe.
https://twitter.com/Bazreynolds9707/status/1245333294390140929/photo/1 here is a link
They have plenty of cash in the bank but the share price came down as Neil Woodfords old fund sold out last week (Confirmed via RNS), was 3.4p only a couple of days ago
Consolidating nicely for the next leg up
Race is on and now the market awaits an update from Nigel ""Developing a convincing proof of concept data package for Nuvec® is a key priority for the Company so demonstrating whether Nuvec® is capable of loading a plasmid DNA for the Coronavirus provides an opportunity to show the versatility and potential for our Nuvec® delivery system, and to license Nuvec® to partners looking to develop vaccines for this virus."
agreed, that latest auction has brought the price too low. i would expect siginificant buying at 7p
Rerate will continue as we have a lot in front of us, AGM and the present collaboration "collaboration with Nanomerics we will be gaining access to scientists and laboratories with considerable expertise in the field of nanotechnology delivery system development and testing. GLA
I have some of these in my Drawdown pension - whoever said "patience is a virtue", is spot on!
Over 6 to sell.The re-rate is well under way now.Was way too low for too long there
Trades going through on NEX too
testing 6p. see where this goes.
We seem to have gathered momentum here.With the tiny Mcap this moves fast.
We are at the start of the cycle, and it happens that Nuvec is ahead with its innovative vaccine delivery system. All will be revealed before the AGM.IMO
I think Pharmas will get a lot of investment now, especially from the governement. Covid19 has exposed so many medical gaps globally, this will now become the biggest growing sector.
Everything on AIM has risk, that’s no secret. The reward vs the risk has to be contemplated on every investment. This has risks (as do all pharma buys) but I honestly and genuinely believe this could be a belter!
ThaiFly you are correct that has indeed been the trading pattern since last April when Nuvec rns'ed inconsistent results (result of lab bad practice by external parties). 2 months before that, in Feb, they raised 1 mill at 10p.
As a result of going back to the lab at UOfA, N4 now has documented the correct processes and again confirmed good results using multiple injections. Has also partnered with Nanomerics which includes use of the facilities at UCL.
After a solid year in the lab I feel N4 & Nuvec is now in a much stronger position that when they raised at 10p. The gains were held into the close on Friday and i think a break back towards a higher range now looks very feasible.
After all even 10p is still only 10mill mcap which in all honesty is not very high for such potential?
bidnolid..................hughwilson but he's a bit persona non grata these days. Long term holders will know why!
Now theres a blast from the past....................ive nothing against N4P just beware the rampers , seen it too many times before with N4P gets ramped/MMs up to 6p or wherever ,investors buy then get locked in when it drops back down to 3p
I/m sure we all know how it works
Covid aside...It’s easy to forgot that we once co developed Nuvec with Medimmune (AstraZeneca) as a partner who pulled out due to a set of inconsistent results. It seems we were very close.
It has since been proven why these results were inconsistent and the process has been addressed. Since then we’ve also made strides in other areas, GMP readiness etc.
Each time with tested in vitro the results have been very good. The last time we tested in vivo the results were very good using multiple injections. The phrase from the results paper was ‘better than existing products’
Nuvec is in a better place than ever which is why I and increasingly others see the current 5 mill mCap as a huge buy opportunity
IMO I don’t think it will be too long before they strike a commercial deal.
All eyes are on an effective vaccine for COVID 19. If N4 can clearly demonstrate that Nuvec is a more effective delivery vehicle for a vaccine (no liver damage being one of the main USP’s) then it will much more easily put them in the spotlight for multiple commercial talks.
All major Pharma’s will want the best solution to this global problem.
The lead time for any vaccine getting to market is 12-18 months. Plenty of time then for Nuvec to illustrate its advantages in the lab. No doubt this lab work will be accelerated as quickly as possible.
Further details to be released soon as per rns.
Leister I respect and thanks for your technical input of where we stand and the future we have with Nuvec and thanks to Abraham to point the validity and the urgency required for a effective solution and rollout to fight this terrible virus. Good luck to N4p and holders I think it's no longer a day traders stock , been here since last three years always been hopeful.
Abraham makes a very good point.
It actually feels Nuvec is behind to join the race for a Covid-19 vaccine but looking at the bigger picture N4 have only one main focus right now and thats completing the data package.
N4 needs to continue getting coverage/noticed showing they can protect dna/rna within the spikes and get it into the cell, eventually they'll surely get taken seriously as a novel nanoparticle company hopefully attracting collabs/partners along the way.
The market for improved delivery systems is phenomenal, the business model for Nuvec could generate some serious revenue if they can improve the dispersion which in turn should improve efficacy. This will show some major advantages over lipids for targeted tumour therapies.
Remember, Nuvec is soley the drug carrying particle and that works consistently each and every time without fail, loading the particles with the nucleic acids (macromolecules) consistently is where Nanomerics hopefully show their expertise. Nanomerics must see the loading capacity combined with the low toxicity and the fact they've confirmed that it works for both DNA and mRNA delivery as now a low risk venture, the worst of the basic stuff is done and ticked off so its now just fine tuning loading.
Im still betting it'll be a cancer immunotherapy project that brings the first paying customer! Clearly a viral vaccine collaboration would be great too :)
Bidnolid - I’m not on Twitter but if anyone here has any thoughts I would be very interested.
Mazik- agree it makes sense for n4 to get involved and test nuvec with ANY vaccines and of course the Covid 19 vaccine is the most urgent right now so it makes sense. My question was not meant as anything negative against nuvec or N4 as a company, I would just recommend a bit of caution for anyone influenced by rampers (not saying you are a ramper) implying that this is huge and nuvec will be used to deliver a covid 19 vaccine. Human trials are already underway for covid19 vaccine and I’ve seen nothing to suggest delivery of the vaccine into cells (which nuvec is supposed to help) will be a problem. There may well be vaccines in the future that require nuvec and if nuvec can improve delivery of vaccines in general then it may in the future be used as the industry standard. However due to the urgency around the covid19 vaccine if it can be delivered using current delivery methods and be effective then that is what will happen imo.
Abraham u have a point , cure for this virus could take time and so does the vaccine delivery system...if u are involved would you not get involved to make success of Nuvec a universal vaccine system and take the share of £210 million.imo
It's a great question. If you use twitter you'd be well advised to post it on the #N4P tag as there's a bloke on there who thinks he's got the answer for everything. He used to post on here under the name hughwilson but he's a bit persona non grata these days. Long term holders will know why!
If all other flu vaccines are delivered effectively with current delivery systems why would nuvec be used with this vaccine? Surely adding a new delivery method increases the complexity and potentially extends the timelines. Nuvec may well become Widely adopted in the future I just don’t see why you would use it now when the focus is on just producing the vaccine as quickly as possible.