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Would have more than to date. I strongly suspect Mr Newland want's "top dollar" for any deal. This is based on the Parsortix machine being probably the best way to catch a circulating cancer cell for assay tests etc. Also as I understand it 99% of the captured cells are alive and intact, you could hardly get a better sample to test. Also Angle are a relatively small Company so could easily get overwhelmed with orders (perish the thought!). One of the good things about the Bioview contract is obviously both Bioview and Angle want to find a big partner so both sales teams will be busy and Mr Newland will be closely working with the directors of Bioview on any deal.
You only have to look at the last few Astrazeneca annoucements to see the industry desperately needs a way to find our if a cancer is HER2 positive, HER2 low, or HER2 negative before, during and after treatment. At the moment after the initial biopsy it's anyone's guess whether a cancer will remain HER2 positive during treatment. If not, as I understand it, the treatment simply won't work and no-one would know for weeks/months.
All IMHO.
Newland’s “hype & hope” strategy is wearing thin.
Bantham
At January's Investor Meet Newland was playing with words deliberately being vague..what he said is that outside of breast cancer testing, my understanding, labs could use Parsortix to test for other cancers so long as they sort accreditation from the FDA, otherwise Parsortix could only be used for research purposes only. Hence how many lab are going to spend considerable time and cost to gain accreditation for a suppliers machine, answer few if any!
It was a truelly ridiculous statement made by Newland deliberately designed to pull the wool over investors eyes!
This explains why no commercial deals of note to date and highlights how Newland deliberately misleads and misguides investors.
We definitely need some substantive news around commercial progress. Without that then the concerns might not be around the fundraise, but the lack of being able to get one away. I’d imagine the market will want some concrete evidence of commercial progress, details of which are worryingly vague in my opinion. All feels a race against time.
Hi Miavoce
Commercially - i agree. Shareholders do not need to understand in order for Newland to close some deals.
But it’s a point of basic communication. Why not make it totally clear to your shareholders? I mean if it is as you think, allowing this confusion is just id1otic when you would think you need a strong share price for an equity issue in due course.
And the fact that Newland hasn’t closed any significant deals ( yes i do know about the $250k Eisai ) raises questions doesn’t it ?
Hi Bantham
I expect that CLIA labs are not confused and know exactly what they can and can't do. This is all that matters (not the confusion cased by disinformation spread by ill intentioned posters).
The fact that this confusion exits is symptomatic of the failures of communication of this company.
It should be crystal clear from Angle’s communications exactly what can and cannot be done today and what that means commercially. It should be very simple to spell this out.
I admit to being confused on this point.
It’s very basic and very important.
Wrong TGTD. CLIA labs do not need FDA approval to use parsortix for testing any cancer types. As long as the labs have validated the tests that they are offering then there is nothing stopping them from offering the test. This is why Angle are developing the Ovarian and Prostate tests (clearly there would be no point them doing this if lack of FDA approval would prevent the tests being carried out by labs).
Miovace
There is a distinction between a clinically approved lab and one that has accreditation to use the Parsortix machine for testing cancers other than breast cancer which requires FDA approval for Parsortix to be used to 'test' and diagnose other cancers and provide guidance on drug treatment.
Think you are getting confused between a clinically approved lab and the Parsortix machine being FDA approved for testing usage regarding wider cancers.
Here you go TGTD - approx 320,000 CLIA approved labs in the US. In due course, once they are fully developed by AGL, the subset of these labs that are commercial labs could provide the Prostate and Ovarian tests using parsotix.
https://www.cms.gov/medicare/quality/clinical-laboratory-improvement-amendments#:~:text=In%20total%2C%20CLIA%20covers%20approximately,for%20implementing%20the%20CLIA%20Program.
Miavoce
And exactly how many labs are clinically approved to use Parsortix to test cancers other than breast cancer?
Let that sink in because you don't know do you..let me help you....ZERO!
Let that sink in let's deal with 'facts' not what you think actual facts, a link showing the number of clinically approved USA labs that can use Parsortix for testing cancers other than forcbresr cancer.
You get very easily confused between using Parsortix for research purposes only versus live testing for cancer diagnosis...
You've been told this a hundred times now you have no facts!
That is my understanding miavoce and the reason for my question a couple of days ago.
Parsortix harvests the cells and then a downstream assay determines the HER2 status - sequential processes. The laboratory accreditation should supply the validation necessary to apply results to determine the treatment regime.
However, as another posted MBC is probably the most prolific form of cancer so, sadly, no shortage of patients.
Parsortix may also have a role to play with solid biopsy samples - I remember an RNS a number of years ago where a research department was having success with a process whereby solid samples were, I think the term was dissociated,(think blender or smoothie maker!) and the resultant slurry was then run through a Parsortix cassette, apparently with great success. This had the potential to short circuit the normal process of preparing and examining a number of microscope slides to detect CTCs using fallible human eyes.
Let's hope that Parsortix can play a vital role in what could be a game changer with AZNs new treatment.
All IMHO
That
?????????????
Dare I mention.
This clip reminds me of the message board here. I’m not sure who is play which role but jesus there’s some weirdos knocking about just posting the same drivel hour after hour!
https://m.youtube.com/watch?v=1nSYZVsHnVU&pp=ygUSc2NvdHRpc2ggcHViIHNjZW5l
Status of patients cancers during cancer trials let alone anything else. Obviously drugs that target HER2 positive cancers need to be given to people with HER2 positive cancer! Then the cancer's status needs to bo monitored during treatment to see if it's status changes to for example HER2 negative, in which case the treatment could be changed.
Two possibilities just from Astrazeneca in just the last few days!!!!!!!!!!!!!:-
https://www.lse.co.uk/rns/AZN/fda-accepts-dato-dxd-bla-for-breast-cancer-6gb18korpqpp8bb.html
https://www.lse.co.uk/rns/AZN/enhertu-approved-in-us-for-her2-solid-tumours-d992ucbs0xpl3ik.html
All IMHO.
TGTW, how many times must I tell you this. Parsortix can by used to clinically test any cancer when the test is developed and undertaken by a CLIA laboratory - no need for FDA approval. This is how the prostate test will be delivered for example. Also parsortix can be used to support clinical trials of any drug in any cancer type. The Angle labs are ALREADY doing this.
Read slowly and let it sink in.
FACT!
Without FDA apprival to test most cancers why would labs waste time and money investing in a testng machine that's not fully FDA approved!
Https://accessgudid.nlm.nih.gov/devices/search?query=parsortix
Better website with same info
- So gained 26.67% over Mon and Tues.
Now down 11.1%.
26.67 - 11.1 = Up 15.57%. Should not complain!
Https://fda.report/Company/Angle-P-L-C
is this new info? Seems like product specific filing rather than over all?
ANGLE plc
LON: AGL
OverviewFinancialsCompare
13.75 GBX −2.00 (12.70%)today
Should have gone to Specsavers big discounted sale on!
I did warn you same as January!