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Remember 37p in Jan. Seems AN and IG like to give it the old one two when it comes to news. Another coming along shortly?
Good RNS today and ANGLE very much in the spotlight with what's in the media today.
As for the share price this really sit over 25p in anticipation for key milestones coming in.
Taken some as I reckon this revisit 150p with the pipeline it has.
Could also recieve a takeover offer at substantial premiums.
Hear! Hear! FT
Question for Board and management team:”Is Angle actually now just an academic research unit? “ like other investors, am absolutely fed up with a continued pattern of behaviour from Newland - announcing BAU non-price sensitive meetings, hyping minor commercial agreements, & signalling world class results on tiny cohorts. When does this stop, Andrew? When do you start to behave like a responsible CeO and deliver some meaningful commercial progress? This is just vapourware ; where is the commercial news you promised to back your tripling of revenue forecast for 2024 of £6m?
Price has firmed up here and well oversold.
Goodbye.
A pointless RNS of no value.
‘ We look forward to discussions with translational researchers and industry representatives at this conference to explore opportunities for sales, collaboration, and partnerships.’
How about an order which gets some revenues towards the £6.6m promise?
Is that even Angle?
Hello.
EC
Why are you spamming the BB it's just copy paste all day long with you!
Correction. Spelling errors and "CCT" accidently used instead of CTC (Circulating tumour cell).
Https://www.ft.com/content/d146dc71-3060-4bc7-bb1b-d60c24193e14
Grail offer the Galleri Test that helps screen for cancer. From a search on google for "what does the galleri test do":-
"The Galleri test analyzes cfDNA fragments to detect abnormalities in methylation patterns that could indicate the presence of cancer. Galleri has been trained on the largest known methylation database to identify patterns common to many cancers.". This is a state of the art test, currently available to help find out if a person has cancer.
Once a person has in their blood "circulating tumour cells" (CTC's) obviously they already have cancer and have had for quite some time as CCT's don't come off the original tumour in the early stages (I think until around stage 4?). Angle's Parsortix machine can catch CTC's, 99% of which are LIVE and intact, ideal for testing in the same way the cfDNA fragments are. Angle are suggesting that similar tech is applied to test CTC's which would give valuable additional information about the state of a persons cancer as treatment progresses. So a test before any treatment to establish the base line. Then tests (every few months?) during treatment. The test would be both to monitor the cfDNA fragments generally in the blood AND to test the CTC's. Both tests to obtain all the information available about the treatments effect. The aim being to find out as soon as possible if the treatment is starting to work, or is having zero effect. If zero effect clearly the treatment could be stopped and another one tried. Receiving treatment that IS NOT WORKING is obviously very, very important to know. This is what Angle are suggesting. Makes sense to me.
All IMHO.
Https://www.ft.com/content/d146dc71-3060-4bc7-bb1b-d60c24193e14
Grail offer the Galleri Test that helps screening for cancer. From search on google for "what does the galleri test do":-
"The Galleri test analyzes cfDNA fragments to detect abnormalities in methylation patterns that could indicate the presence of cancer. Galleri has been trained on the largest known methylation database to identify patterns common to many cancers.". This is a state of the art test, currectly available.
Once a person has in their blood "circulating tumour cells" (CTC's) obviously they already have cancer. Angle's machine can catch CCT's, 99% of which are LIVE and intact, ideal for testing in the same way the cfDNA fragments are. Angle are suggesting that similar tech is applied to test CCT's which will give valuable additional information about the state of a persons cancer as treatment progresses. So a test before any treatment to extablish the base line. Then tests (every few months?) during treatment. The test would be both to monitor the cfDNA fragments generally in the blood AND to test the CCT's to obtain all the information available about the treatments effect. The aim being to find out as soon as possible if the treatment is starting to work, or is having zero effect. If zero effect clearly the treatment could be stopped and another one tried. This is what Angle are suggesting. Makes sense to me.
All IMHO.
BOJO - take a look at the two year and one year share price graph for Angle.
The first thing you see is a one way substantial down trend. That means anyone who believed in Newland and held their shares as a long term investment lost a lot of their investment - on paper at least.
The second thing you see is multiple price spikes ( you need to look at the one year graph aswell as they get lost in the two year). That’s where the company issued some exciting update / breakthrough and the rampers ramped. The rampers knew what they were doing and sold at a profit. Even EC sold some shares during the last ramp for goodness sake because he isn’t a fo0l [ BTW i am not criticising EC - i don’t consider EC as a ramper - i think he’s a real believer ]. But the rampers sucked in gullible punters who were more likely to lose money - it’s actually an example where what’s written on this site and ADVFN does have an impact on people’s behaviour sadly.
This is not ‘ normal share price behaviour’ as you suggest. It’s a company which IMHO hypes announcements which appear to actively encourage rampers and leads to losses for the unwary.
So i don’t get the criticism of those of us who simply suggest there is enormous risk to a long term investment here. To me it is just a statement of the obvious.
DYOR etc etc - but the share price graph isn’t a bad place to start.
EC
You seem to be deluding yourself that Big Pharna would be interested in buying AGL.
The point you fail to address is why isn't the Parsortix machine selling...The answer is very simple labs want machines that can test for all cancers not just one and there in lies the reasons why the Parsortix machine isn't selling, hence no material commercial deals to date, the Parsortix machine is FDA approved for testing one cancer group, only 4% out of the 25 or so major cancer groups..No FDA approval means no sales...spin it as much as you like but that the reality here I'm afraid!
If anyone is credulous enough to believe any of the nonsense spouted by posters, here or elsewhere, and to make investment decisions based on it, then they deserve what they get.
MOAB
Bantham,
You say that people get sucked in by the rampers and get spiked and end up selling low. You add that it happens multiple times... So what you are saying is that the price goes up and down repeatedly. Well brace yourself as I have too inform you that this is quite normal share price behavior! I would also add, you simply don't know when others buy or sell.
I don’t understand your point aimgambler.
The only way people lose money is when they get sucked in by rampers and then sell at a significant loss when the hot money leaves. This is exactly what happened to a lot of people with Angle. And it’s happened multiple times.
The only people who make money are the rampers who sell while they are ramping. Maybe your comments should be aimed at them?
None of us our short - that would be nuts on a volatile stock and I’m not even sure it’s possible for Angle. If it is perhaps you could explain how to do it? We just think if you invest here ( rather than trade on a ramp ) you will lose money.
Bit of red and the shorters see profit and post whatever they can dream up to strengthen their trade. Rumours, downright lies, it doesn't matter anymore as nobody is going to arrest them.
It's now become rife on AIM.
Personally I think it's very sad, as it's an indictment of society today, where a sizeable minority will take whatever they can get regardless of who they step on.
I give it 3 years and AIM will be completely finished.
The joke used to be that it was like a casino. It's now much, much worse.
Aimho, dyor, etc.
TwoGood2Die.
"Probably because Illumina have their own solution and no one is buying any Parsortix machines because they are not FDA approved!".
===============================
Lying again I see.
"Illumina have their own solution". No they don't, not as good as Parsortix. Lie Nr. 1.
"no one is buying any Parsortix machines". Lie Nr. 2.
"they are not FDA approved!". They are approved for use with Breast Cancer in the USA as you undoubtedly know. Lie nr. 3. Shows the sort of person you are.
Also they do not have to be approved for cancer research. Lie nr 3a.
Are you capable of posting a single sentence that has any truth in it at all? I suspect not.
Surely no-one on here listens to anything you say considering your track record.
All IMHO.
EC - i mean objectively a track record of failure.
Who set the original expectations of Parsortix sales? Newland.
Who, nearly 2 years after FDA approval has secured no orders of any materiality? Newland?
Who, having set a sales target of £6m this year, has announced virtually no new orders to support that target? Newland.
Who has spent nearly £100m - or something of that sort - getting to a position where there is zero evidence of real commercial traction? Newland.
Doesn’t sound like success to me.
Maybe there’s one area where he has succeeded - as a kind of cult leader promising his followers that he will get them to the promised land despite all evidence to the contrary. And getting some people to believe that.
Probably because Illumina have their own solution and no one is buying any Parsortix machines because they are not FDA approved!
Bantham.
You say " Newland has a track record of failure.".
Presumably you mean the failure to sell anything like the amount of Parsortix machines originally expected?
Last year, I think that without any assays to go with it (so the client had to do them) or standardised staining kits the expected sales of the machine were totally unrealistic. Now of course Angle have developed some assays and staining kits that they offer to sell with the machine making it more user friendly. Also they offer a service from their lab which uses in house Parsortix machines to catch and analyse circulating tumour cells (blood sample sent in from client) in many, many different ways. Including the molecular analysis that Mr Newland described as "a game changer".
Indeed this side is extremely interesting and, at least at the moment, I too believe the molecular analysis side really could be a "game changer" for Angle. Seems to make sense. Companies like Illumina and Thermo Fisher already sell machines that analyse a standard blood sample for so called "actionable DNA variants". If found these already known DNA varients can give important information to the clinician about the cancer helping treatment decision making. Now as we know Angle have made the breakthrough that using the same process on circulating tumour cells (ctc's) that Parsortix can catch can give important ADDITIONAL information for the clinician. Presumably this is accurate and totally up to date information as the circulating tumour cell will have come from the cancer tumour looking to seed itself somewhere else in the body. As Mr Newland has said these Companies could offer Parsortix to their existing and new clients who may well want this additional information to get all of the available information, the "Full Picture". Obviously Mr Newland could do some sort of deal with one or more of these companies and I don't see why they would not be interested.
All IMHO.
EC - Newland has a track record of failure.
He has burned through £10’s of millions to date and has made no significant commercial achievement.
He also appears to have alienated any half decent Institutional Investor. At least there are none on the register.
If he can’t get serious investors into the stock why do you think some corporate will pay a big premium?
Honestly - Newland has never done a decent deal so i really don’t understand why you trust he ‘ won’t sell on the cheap’. I think there are zero corporate buyers for this ( the evidence being that if they were they would have taken advantage of what you believe to be a very low share price ). However, let’s pretend for a moment that there is a buyer. Well in that case if a proposal were made he would have to take it at pretty much any price as his alternative will be to raise equity and he doesn't have the investors to raise £millions from as it’s a retail / day-trader register.
My impression of Mr Newland is he's not one to sell anything on the cheap. Possibly quite the opposite in fact. I have done more reseach on the Parsortix system. It ticks all the boxes. Other products can catch circulating tumour cells but Parsortix is quick, 99% of the cells collected are live, intact and not contaminated by the very system used to catch them. You can't get a better circulating cancer tumour cell to test, period. Angle only need half a dozen contracts on the assay side and things will be a lot different. And that does not include the distinct possibility one or more of the molecular analysis Co's will want some sort of deal, maybe even buy them out. We can be sure of one thing. Newland won't do a deal on the cheap. I just hope he does not ask so much no-one will bite.........
All IMHO.