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No one in their right mind would be selling now, except RiverFort. The BoD need to wake up and address the whole financing issue. Their silence on this matter, and their lack of urgency, I'm finding completely unacceptable and disrespectful. What in heaven's name are they playing at? Get a grip!
Most likely RF trying to recoup some £s
Need finances sorted ASAP
0.0035
Maybe we could have an investigation into who is shorting this.
We have net £25k of sells today for a near 20% sp drop.
Somebody continues to trash this
Not convinced Sareum will still be around to convene an AGM (usually in December). An EGM is what we need.
If we are still here by the next AGM in december one would hope everything will have been resolved here ... !!! - lets hope so
The next AGM is not going to be easy for the Board... I think a vote of no confidence is needed, but what next, and what else needs to be done by us shareholders?
Physiomics today announced that it has been awarded a substantial new contract by its existing and largest big pharma client. The project involves pharmacokinetic-pharmacodynamic (PKPD) modelling in the field of DNA damage/repair field and will help inform clinical dose and scheduling decisions.
Just woke up this morning thought , it’s Monday , new day, new start. Besides, it’s Ramadan , though I am exempt from fasting because of various ailments I am blessed with. So anyway thought to look at the Sar SP. I did, and immediately burst into laughing, and I laughed. I know what I saw was sad rather than funny! I know there is hope yet, and it’s not over until the fat something sings! But I can’t explain the laughter, maybe I am going Mad! Best regards to all.😅🙏
I am heavily invested and significantly down. I therefore have absolutely nothing to gain from this post before I am accused of shorting and deramping.
I understand the need to cling on to some hope. However, the reality is that this company has been terribly managed and we have reached the point where we can't even secure death spiral financing.
Posting dozens of links to studies doesn't change this. Getting angry at shorters doesn't help.
It pains me to say, but we are highly likely going to lose everything. I'm not selling because I don't know for certain. But I think some of you need a reality check and to tone down the endless bombardment of ramping which is probably the reason some of us are now in this situation.
0.35p old money ... what a joke
Morning C79 and thanks,
8. Unveiling the Landscape of uncommon EGFR Mutations in NSCLC - A systematic review:
https://www.jto.org/article/S1556-0864(24)00123-0/fulltext
ATB
Morning all, apologies if any links have been shared previously:
1. TYK2 signaling promotes the development of autoreactive CD8+ cytotoxic T lymphocytes and type 1 diabetes:
https://www.nature.com/articles/s41467-024-45573-9
2. New Data Reinforce JAK Inhibitor Efficacy for the Most Challenging Types of Alopecia:
https://www.medscape.com/viewarticle/new-data-reinforce-jak-inhibitor-efficacy-most-challenging-2024a10004tv?form=fpf
3. Psoriasis biomarkers modulated with TAK-279 treatment:
https://www.healio.com/news/dermatology/20240315/psoriasis-biomarkers-modulated-with-tak279-treatment
4. Targeting oncogenic kinases: Insights on FDA approved tyrosine kinase inhibitors:
https://www.sciencedirect.com/science/article/abs/pii/S0014299924001729?dgcid=rss_sd_all
5. Practical Use of Upadacitinib in Patients with Severe Atopic Dermatitis in a Real-World Setting: A Systematic Review:
https://www.tandfonline.com/doi/full/10.2147/CCID.S329442?src=exp-la
6. Interesting piece on the development and timescales of Momelotinib's journey to the clinic:
Momelotinib for myelofibrosis: our 14 years of experience with 100 clinical trial patients and recent FDA approval:
https://www.nature.com/articles/s41408-024-01029-3
7. JAK-STAT Signaling and Beyond in the Pathogenesis of Spondyloarthritis and Their Clinical Significance:
https://link.springer.com/article/10.1007/s11926-024-01144-x#Sec14
ATB
Robin....
Its a tough time for pharma/biotech or many small comps. And SAR need to get into that 1b zone to produce data from humans. That's a common sense reading. Unless someone knows a lot about these kinds of compounds and see value here, at this stage. I'm not a pharma/bio PHD so I can't comment on that.
I'm pretty sure the maths for the shorters is a sub 10p stock. But I always like the possibility of a left-field play - and the maths for anyone trying to play guardian angel with seven figures plus - I imagine that maths is changing on a daily basis.
We shall see. Certainly post-placing there will be a flood of buys - but thats cold comfort, I imagine, if you are already underwater.
Thankfully nobody listened to that guru (M0ron) and held their nerve. Gla x
Carter I never sold one share thought gone past this stage price held up quite well B4 we had those two disastrous events, ie RF consolidation & oh peel hunt, let's hope prey 🙏 this gets sorted
Rgds
Ray
Can’t believe you never sold gunner
You got me on that one. I have no idea.
I see no reason why there should be a lack of information on this as Sareum has 27.5% financial interest.
Acrivon raised 100 million dollars for discontinued Prexasertib as related to myocarditis.
737 there was not an associated problem.
All very quiet on this front.
Not of benefit to Sareum if they were pinning their hopes on much larger upfront payment.
I would expect update or confirmation here in first week of April. Around 3 months from start to finish to agreement finalisation.
Regards
SAD and where is the money from the 737 deal so far ?? We had nothing to do with it we have had our pants pulled down again nearly 3 months in and not even signing on fee as the deal has not been done the only ones getting done is us
GLA
Hood,
A licencing deal sonny does not involve dilution.
Let me carefully put to you.
A licensing deal consists of an upfront payment, followed by milestone payments.
Please explain where the dilution comes in.
Hood,
I will keep it short especially for you.
The compound CCT245737 was developed by Sareum in partnership with the ICR/CRT
Regards
Hood, you are getting desperate sonny!
More utter garbage from you.
It’s a heavily discounted placing or a one in a million shot of some kind of non-dilutive funding like a licensing deal. The Holy Grail for small cap pharmas that never actually happens in real-life, especially to companies who don’t have any efficacy data.
Take a look at CCT245737 compound that was licenced a while ago.that was in phase1 clinical trial being of safety profile only. No clinical efficacy results as phase 1.
Upfront payment was smallish but total including milestone payments was circa 300 million.
So they do happen and not once in a million probability
Regards
Are you some kind of Knuckle dragger or just stupid, what I or anyone else does on here is none of you business, jog on you bore.
I wonder about the bucket shops. Yes that might happen. But it might not. They might have someone they can touch on. They managed to get some interest in 737 - so there are channels between SAR and £ (or in the case it was $?). See what happens. I do feel they are a bit cr*p - as many have said, why on earth didn't they raise when the sp was high - it makes sense to raise when you DON"T need the money - and I don't think enough AIM companies do that. Anyway lets see what happens next.
Doesn’t blow my mind at all, might blow yours because it doesn’t!
Unfortunately my mindset is different to yours, which obviously brings your aggressive narrative to the bb, I invested my money in Sareum for them to succeed and I have covered my investment with profit for which I’m grateful, still hold a balance and hope they progress, scientifically I think they are doing well, financially, due to s **** like you they are currently in a “Piccalilli”, hopefully, they will resolve of their own accord, rather than self acclaimed “saviours” and as I said earlier, hope you and your family never have the need to regret the downfall of a Company like Sareum and the intentions in what they are trying to achieve over a few quid!
Knowledgable or not as a reasonable human being, I hope they succeed - good night!