has completed development and validation of a new test for pancreatitis in dogs.
Pancreatitis is a very common inflammatory disorder of the pancreas in dogs of which there are 83 million in the US and 8.5 million in the UK. The acute form of the disease occurs in around 1.5% of dogs whilst the prevalence of the chronic form is reported to be as high as 30% suggesting a large market for a pancreatitis diagnostic test. However, the market is even larger than the prevalence of the disease alone would suggest because most dogs with pancreatitis present with common gastrointestinal signs of upset, such as vomiting, anorexia, painful abdomen, hunched posture, diarrhoea, fever, dehydration and lack of energy; with vomiting being the most common symptom. Consequently, a much larger number of animals would be screened for pancreatitis than may eventually be diagnosed with the disorder.
Avacta's new pancreatitis test utilises the same approach as its unique canine lymphoma blood test in which an algorithm is used to combine the results of two common blood tests with other symptoms and other information about the dog such as age and breed. Currently there is only one other proprietary test for pancreatitis in the market. Avacta's internal validation of its new pancreatitis test performance shows that is has better sensitivity, specificity and predictive capability than the established test when tested on confirmed pancreatitis cases clinically diagnosed by vets at a large referral centre in the UK using other techniques such as ultrasound.
Avacta will commercialise the test by providing "pay per click" access to the diagnostic algorithm which will allow veterinary laboratories world wide to get an accurate and immediate diagnosis for pancreatitis by submitting the results of two blood tests commonly run in house along with other patient information on-line. In due course the blood tests themselves will also be offered on the Sensipod in-clinic analyser allowing vets to access the same on-line pancreatitis diagnostic.
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