LONDON, March 18 (Reuters) - European regulators have launched an investigation into the safet
y of Takeda's diabetes drug Actos, following a possible link to increased bladder cancer risk.
The European Medicines Agency said on Friday its experts would examine the benefit-risk balance of the drug, known generically as pioglitazone.
The bladder cancer risk has been under close review ever since Actos was approved in 2000 and Takeda is conducting a 10-year study looking at cancer rates in diabetic patients on the medicine.
Three interim study reports have so far have not confirmed a clear association between Actos and bladder cancer -- but the European agency said an increased number of spontaneous reports had prompted it to start the latest review.
Actos belongs to the same drug class as GlaxoSmithKline's Avandia, which was pulled from the market in Europe last year and faces stringent restrictions in the United States after being linked to heart risks.
(Reporting by Ben Hirschler; editing by Kate Kelland) Keywords: TAKEDA EUROPE/
COPYRIGHT Copyright Thomson Reuters 2011. All rights reserved. The copying, republication or redistribution of Reuters News Content, including by framing or similar means, is expressly prohibited without the prior written consent of Thomson Reuters.
Datafeed and UK data supplied by NETbuilder and Interactive Data.
While London South East do their best to maintain the high quality of the information displayed on this site,
we cannot be held responsible for any loss due to incorrect information found here. All information is provided free of charge, 'as-is', and you use it at your own risk!
The contents of all 'Chat' messages should not be construed as advice and represent the opinions of the authors, not those of London South East Limited, or its affiliates.
London South East does not authorise or approve this content, and reserves the right to remove items at its discretion.